ISIC 2018 is the twelfth ISIC conference. The ISIC conferences have a reputation for being an arena for discussing challenging work concerning people’s contextualised interactions with information of various kinds. ISIC is multidisciplinary in scope: researchers from information science, information studies, library studies, communication studies, information management, education, management science, psychology, social psychology, sociology, STS, information systems, computer science, and other disciplines contribute to the research field. A common thread is the focus on contextualised information activities, expressed in different framings such as ‘information behaviour’, ‘information practice’, ‘information seeking’ ‘information experience’ and others. ISIC 2018 intends to reflect and engage with the interdisciplinary character of information activities research and seeks to attract papers from all of these areas. ISIC is a conference for research papers exploring information as a rich site of study, going beyond the sole focus on technological aspects and exploring a wide variety of contexts. This legacy is borne out in the publication of the conference proceedings since the first conference in the series over 20 years ago. Themes of the conference include, but are not limited to, the following: Theoretical conceptualizations of the cultural, social, cognitive, affective, and situational aspects of information needs, seeking, searching, use and sharing. Research approaches and methodologies employing and developing qualitative, quantitative and mixed method approaches. Specific contexts: e.g. in different sectors and organisations (health care, education, cultural heritage, libraries, business, industry, the public services and government, the emergency services and others); in everyday life, and in social networks, including social media, gaming or virtual worlds. Collaborative information practices: communities, boundary spanning and innovation practices. Information use and value: meanings of information and how information is used to help solve problems, aid or support decision-making. Information metrics and analytics, social media and enterprise analytics. The role of information in building and enhancing the adaptive capacity of organisations: strategy and information absorption, transformation and integration. The mediation of information practice: how human or software agents (algorithms) can respond to and support information activities and the design of information delivery systems. Cross-disciplinary contributions: integrating studies on information seeking and interactive retrieval; integrating information science, management science and information systems. Critical investigations of information activities in contemporary society and of ethical challenges. The ISIC conference is particularly interested in analytical rather than descriptive investigations.